Compile Data Set for Download or QSAR
Found 137 of Enz. Inhib. data with enzyme = 'Cytochrome P450 11B1, mitochondrial' and Substrate = 'BDBM8582'
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8871(5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8873(5-[(1E)-2,3-dihydro-1H-inden-1-ylidenemethyl]-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8875((5Z)-5-(1H-Imidazol-5-ylmethylene)-5,6,7,8-tetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 9nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 10nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 10nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8879(5-[(E)-(5-Fluoro-2,3-dihydro-1H-inden-1-ylidene)me...)copy SMILEScopy InChI
Affinity DataIC50: 11.2nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8876((1E)-1-(1H-Imidazol-5-ylmethylene)indane-5-carboni...)copy SMILEScopy InChI
Affinity DataIC50: 12.3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8876((1E)-1-(1H-Imidazol-5-ylmethylene)indane-5-carboni...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8878(5-[(E)-(7-Chloro-3,4-dihydronaphthalen-1(2H)-ylide...)copy SMILEScopy InChI
Affinity DataIC50: 18.7nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8881(5-[(E)-(5-Chloro-2,3-dihydro-1H-inden-1-ylidene)me...)copy SMILEScopy InChI
Affinity DataIC50: 19.5nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8879(5-[(E)-(5-Fluoro-2,3-dihydro-1H-inden-1-ylidene)me...)copy SMILEScopy InChI
Affinity DataIC50: 20.6nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8883(5-[(E)-(5-Bromo-2,3-dihydro-1H-inden-1-ylidene)met...)copy SMILEScopy InChI
Affinity DataIC50: 23.5nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8873(5-[(1E)-2,3-dihydro-1H-inden-1-ylidenemethyl]-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 25.9nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8883(5-[(E)-(5-Bromo-2,3-dihydro-1H-inden-1-ylidene)met...)copy SMILEScopy InChI
Affinity DataIC50: 26.2nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 28.3nMpH: 7.4 T: 2°CAssay Description:A suspension of fission yeast (S. pombe PE1) with a cell density of 3˙10^7 cells/ml was prepared on a freshly grown culture using fresh EMMG (pH ...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8881(5-[(E)-(5-Chloro-2,3-dihydro-1H-inden-1-ylidene)me...)copy SMILEScopy InChI
Affinity DataIC50: 28.7nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8871(5-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)copy SMILEScopy InChI
Affinity DataIC50: 31.4nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN362HPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8917(1-(3-methoxynaphthalen-2-yl)-1H-imidazole | Imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 81nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8583((3-Pyridylmethylene)indane 1b | 3-[(1Z)-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 87nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8587((3-Pyridylmethylene)indane 5b | 3-{[(1Z)-5-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 125nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)copy SMILEScopy InChI
Affinity DataIC50: 127nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB156NPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8641((3-Pyridylmethylene)indane 38a | 3-{1-[(1E)-5-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 159nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM220125(US9271963, 27)copy SMILEScopy InChI
Affinity DataIC50: 206nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445KBNUS Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8596((3-Pyridylmethylene)tetrahydronaphthalene 13b | 3-...)copy SMILEScopy InChI
Affinity DataIC50: 206nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8931(5-(2-Naphthyl)-1H-imidazole | 5-(naphthalen-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 207nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PNTPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8891(3-(6-Methoxy-3,4-dihydronaphthalen-2-yl)pyridine |...)copy SMILEScopy InChI
Affinity DataIC50: 213nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445KBNUS Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)copy SMILEScopy InChI
Affinity DataIC50: 224nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM151585(US11739089, Compound Ketoconazole | US8987315, Ket...)copy SMILEScopy InChI
Affinity DataIC50: 224nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445KBNUS PatentDrugBank
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)copy SMILEScopy InChI
Affinity DataIC50: 224nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM151585(US11739089, Compound Ketoconazole | US8987315, Ket...)copy SMILEScopy InChI
Affinity DataIC50: 224nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445KBNUS PatentDrugBank
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8618((4-Pyridylmethylene)indane 8a | 4-{[(1E)-5-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 243nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8615((4-Pyridylmethylene)indane 6b | 4-{[(1Z)-5-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 257nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8589((3-Pyridylmethylene)indane 7b | 3-{[(1Z)-5-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 270nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8613((4-Pyridylmethylene)tetrahydronaphthalene 4a | 4-[...)copy SMILEScopy InChI
Affinity DataIC50: 282nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8900(3-[(Z)-2-Phenylvinyl]pyridine | 3-[(Z)-2-phenyleth...)copy SMILEScopy InChI
Affinity DataIC50: 288nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM25441(5-(3-fluoro-4-methoxyphenyl)-1-(pyridin-4-yl)-2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 291nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB156NPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8608((3-Pyridylmethylene)indane 25a | 3-{[(1E)-4-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 304nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8586((3-Pyridylmethylene)indane 5a | 3-{[(1E)-5-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 311nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8591((3-Pyridylmethylene)indane 9b | 3-{[(1Z)-5-bromo-2...)copy SMILEScopy InChI
Affinity DataIC50: 320nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8640((isoquinolinemethylene)indane 30b | 5-{[(1Z)-5-flu...)copy SMILEScopy InChI
Affinity DataIC50: 374nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8614((4-Pyridylmethylene)indane 6a | 4-{[(1E)-5-fluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN075FPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8889(3-(3,4-Dihydronaphthalen-2-yl)pyridine | Dihydrona...)copy SMILEScopy InChI
Affinity DataIC50: 411nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445KBNUS Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8895(3-(4-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)copy SMILEScopy InChI
Affinity DataIC50: 437nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445KBNUS Patent
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8894(3-(3-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)copy SMILEScopy InChI
Affinity DataIC50: 503nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FBSPubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

LigandPNGBDBM8894(3-(3-Methyl-3,4-dihydronaphthalen-2-yl)pyridine | ...)copy SMILEScopy InChI
Affinity DataIC50: 503nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q2445KBNUS Patent
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